This program calculate HPLC Carrier Solvents ratio that make 2 molecules retention time wider. You need Hansen Solubility Parameters (HSP) for that molecules, so this program is for HSPiP user.

 

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The basic idea is come from HSP distance.

"Carrier Solvents HSP is near to one molecule and far from the other molecule" that make resolution high.

Please refer to original article in HSP application note.